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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1289d2aace1cc674d30f5a5ebe1a9f74217c5e461298cd14e61e4fecd54f7f' 
  AND token = '2SKY87pwX0MV75WF8BSU+JzwIm24z28nmUPrB+uLzdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}