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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9a4d02339bff01cca76df160c2f3cd1c40c9d630718dfb7354abf0f80891b6' 
  AND token = 'dt2Va2fi55JAzMPqc6WfjfT0ArvYd+owISNyCwD610s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}