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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04da199130fe9575d35c3df6b0e184b7900b1f351f630fdd99f33edd99d0f050' 
  AND token = 'IcjSMro9zrfA+wCPRP1PegwvNMix6GuglnPe4StbPgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}