SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0eaf58d6a4d000a78ea2dfde52aaa821040a1f7ae0a37e8f49b6016bf4ce0e0' 
  AND token = '7z/3wfkh1U8PILVj4vsfHD64dtkd00DUFxgZv1HQ+k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}