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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b1e085abf593b003344e779cc7d6068afb3f7d9fd691300a5a7b9a182fa434' 
  AND token = 'huT/spV7Y7Hetc6Xsh9q3x7imOkNABBMFBlHJiK3r4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}