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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f205232bf311b7ce219fad6e9bbfcbbe4c4dce30ef40d4a20fe69664c8bfa0' 
  AND token = 'aJIHUQ5w+mES8+FAhOP8S8slq5/a/BdEbJygYX0qqDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}