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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83e0565ace6d451994ac3e1824b70b66aa3dc2bda231598ec6728b2df5fbc893' 
  AND token = 'GypOZMRKIZ8pZRR7R6GIfTstTONvjqxl65mfE4eFnEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}