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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b52c1abd503b767c27acb08b1bde98eec194c8f7e41d3e33bef68604434a9f' 
  AND token = 'TwZdBmaXCZfAuf1vKumml/qaJD9iW4gOWdU1LtMCh0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}