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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b8c439ef86ac1bb5669a2c8f98c384f47bc44d7490e09d23781c1048490dda' 
  AND token = 'A5Y/4FpgzCwzYK70RkzHkcJNOd4MSDygYOTjDlvyfWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}