SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38645d81988b7e9f231949b1a0b2be8d3e6425670ce0f5c19025821286e2842' 
  AND token = 'p8OgoRYhTuCqSNY1YREiYItrBu/xA9LlXH/NfyKG2Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}