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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a1cb2750d4d4774855e0ac72615fcb8e00eef1c6f389af2b3903d227b36377' 
  AND token = 'WNX1A+tAitlbdajw8xCEqMEQ8FR1PLsDfSCxga6EcaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}