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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f24aaef5a57cca166cbcabaddcab6351fab2ff668a5534eff7a7e41efb60f04f' 
  AND token = '489bBc+WvUhZSXC0BgA/nMX/GuXCssVKZzBSI4ixcvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}