SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a7a04e9f2f1ca156c7c56ab4f6116d649a735748540bf902eb13cf9ca0e383' 
  AND token = 'kCi9HEkV1SXKvhFbfPVx6BwnBcn6pBomU7tjvO8IR6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}