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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8d1f7c3a0de8c2d89b182f0ea9a8f02ca812e70d22951870dbc05f23a6b443' 
  AND token = 'X6M2ZbOw0zAtoFdVtn5+J+6D0hr7lpTAtPae6W10wec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}