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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b149e6bb95b5e9dd48d2f332a4a5d4322c79ce33fb2b2125bed201cb2da9d29' 
  AND token = 'eP1tCQb3qynArvcEUUdT/N+EyGcXx8JaNtXhOLJWQ04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}