SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5c6e101ceed5294520e4e74cd4aa5602cd59f20aaaef8aa40f5d2ad9c774eff' 
  AND token = 'afZnMP6/X6hGjOSwjQoPJGSiRW4d3sNYiJD3MzaH7qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}