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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f12b17cd529c85f661bdaa9d75aafc24d8c7aa99bd86a40c80b8024d6eade1' 
  AND token = 'aGlKiP4lKNckBVr5xySGlYrg3ZPQe+VUy0CrSWFe4Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}