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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6100e409828dab4b9c4a9186bc7f4421e98ab4b470f3dd6b70d5ce7f8bb6f21d' 
  AND token = 'rtPYrO47ZJoFzH6FG2beWO9KnZYSKA0Ri0vZeop3hDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}