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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ccd39d6cfbddff3caf30714d0eb2b71787aaeb744e569050b440bc9bb45514' 
  AND token = 'AgIY52N63z+ab7E1gAE2U0ay8sWI/MJ92Xr5Ok0IEz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}