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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd61b8423107e74b2d15f970314ebfe71bd4a4f915b58b00035794b43ccdb63' 
  AND token = 'hgMYF+BgvT9yRPOxIjNrre90OlSN3ex41ZGSh0txbOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}