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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709066167f593e95bff48feb9fc14587f5e9bf177a3c7f418f4c944579f8b173' 
  AND token = 'r+icDLWBCtAcr/vEiMQsuvmPIFDWXoKHrrk2j1nLg3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}