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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3049bc5afe150e43d25a1211cd63ba731958da4e98fe29c4b701fafe8c1833' 
  AND token = 'OrbX2LpX7H+fES+ro+fp6kahnp8wjs1MdUO3LFkJH5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}