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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2248cca50e2aaf2aa472062fb466958739e9a24d82b21f7f354e4d8a743bea94' 
  AND token = '+liSRjtsWpP0N1VdY0UHea/vxqsXJIn19C/u3Gjyw4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}