SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3bb7c26773afd5bb8d30d3c052c189b5d62f7a2d4b0774290c107bb56c213ac' 
  AND token = 'EF2jGwL6m07yx9RuCvYCZcRYBfFm1rELAJlsTZfwzEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}