SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8ccbd3b414439c3874b837c7e924d7a16dd05953d73940adcb2285fc350878' 
  AND token = '+Ssz7v/KrI+a5teE4vDgc1uh2GH/ubTS2+K+GxPt/fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}