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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18db6273038f09dd090e1c24612322fe8fbe62f3c168b6533adf1b5a14fb3711' 
  AND token = 'o+gId9w7eL0O+qlt9koeWrZuv3atWUTkeDPxmQFb2L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}