SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922d67122c3bd48e65f88285a9a5e7d1edeeb97e1a97ff4619972f9f8a5e8291' 
  AND token = 'AnXbRVOdSaxpEwC2qD1+uolJhEIw6q1fZEJ84Ox2HTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}