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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9ac0b1c74cd9f13dca7925553dbd12eefba3b34ef380be7de15a9175e7217c' 
  AND token = 'uR1YT36wxi9jaiEpZi8Zr0R2HWRt0no56Iy7UTvlkBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}