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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab8339f2024b1ffaa1c4dcaaa838b003f777d1d629308293c28dfd52da99a42' 
  AND token = 'H2TPDdj1Hu36+qxsirBzJr6y1w785+ajmU9je/qlzgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}