SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25559b87b3e66475e48d136445eb827cbed027623c9b8d6cef8d5d22e0c5188' 
  AND token = 'DZAnAXAnX+HL62TM3HXks7AZpuNZ/VlZoIoMx45dX4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}