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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c6ffa8b70a5e48aa54495d2206047029288c15cce1b0ad6972d3b7c63b00cb' 
  AND token = '+opr1wfU3WReMXxHxo62xVJZMbXxE9qzPQ2U/zIUio0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}