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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c832448dc1ad923e437e7e5fac0de011f2b3bfcdafb776466bd2e4b0463c42' 
  AND token = '8iK14nreyE/LeTktZTiMjHjNMUyFPQy2eY7SSV3GeRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}