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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906e5f08375b0602e71a78e161dedc9781aa6babe4a99c01aa814325eaa1fa8a' 
  AND token = 'GNF8TwvUiJkXjrSsbwpqhhMcXEP1uZr9N9p8w2fvq2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}