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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ca1fd3646f65221e71f912bd0cb3b716d2954cfe52163aa4a2a4caf38641f7' 
  AND token = '3Sb3ZmFJ5wlnyvvcqFe2wHXInwfw3nJQQR0BVsWQ8po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}