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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbb369fc367ae653f233b47d10a3eb3b6c4da2a995c366c63cf2d52a02636b1' 
  AND token = 'dZeHKAe+XqlURSIDIvcdNgtt6s+N+lmM/uz3pd52suk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}