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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43e9876c21ba5167ab63c52c7331b343881fbaf86e228cc634087881f1db93c' 
  AND token = '0eE3DIk6TGBMNSb+ek/IEEwvwNhDW70sLZ5gw36L3GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}