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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b489e1e920459f2428ef9c53002643059851ce43e425156f2d5111acb0ef4c8e' 
  AND token = 'u9ofpTiMUTmFZ6eM82gCnVHtxNlm4L6zzN34yM0/9FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}