SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af37e5f2c5d6463df374ee6f24ec8ba76fe1a0f2ee938ce8d14df2227040238' 
  AND token = 'YUJxCK0m2yS3Fnfh70d2O/CdIZM9kp/lW9mG4rq1qYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}