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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68c995ca17e52caf6eedfb649a7c5145bf6cf6d4643698a131d3393e7c342dcc' 
  AND token = 'gURdYom7RSNsd9p9oLRjbBzzsiUVtZ5wXL1ZxemymQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}