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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f6fb498d42c084f491a48ede40843d08fc5be1c3e7a63f3f62299946cc397aa' 
  AND token = '4u1iYCw4YD9F69ZUawwDrmJ44Xqs7l/lyk1vrOCbnWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}