SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3d8b036acfc0af169a9b998b57e17d82d7d8f38a2722d0e55c01413ca529d1' 
  AND token = 'ZQCHe3h8BEw7BOBJeiM8dsoq574w1ubJFw+bQl8xrVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}