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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4121f24870b6449ce782e73ee3f6d06aaa59e8553d4fe5d88c341b40a5e313' 
  AND token = 'B5vG6yCnpsjNltbJM47m2nTRMzWwnrH6xE8CwGXOj7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}