SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8785322cffc3bee06c83a219f46bb3cd837afd59bdc680243a9d0bc4131dc4f2' 
  AND token = 'B7KqlCOEcN9o335uhEhk9nUTY8N//82ekoNm3M9VUfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}