SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b10d036efb8a24f5b57cf6e5837e26fcdcdb6954ff0f91d0a6e875196fcf50' 
  AND token = '9P3iUwLrEqgd9wxI6nQ3aAO1ZZHjtfzGb7LanFaNBBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}