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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a0a3c952d3a3b65ae17b0647f8b492b341005ba64d1b22a181285810c24b86' 
  AND token = '4Bj7zfDlxFp1X3Mc8Biw+Z5kfcX8lEriLIGZm2Ge0TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}