SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0c34250f32af380eaf605fd6774a472701ac9abb15080c7f64fb08225b03ed' 
  AND token = '6W0AjeFbtx2aq8iWOP9kLc2V/mUEhQJmTfT4oFzVKuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}