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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2922102e52c168d893fa15a1380721cafc29461b6b29095e37dd6e711557de61' 
  AND token = 'CaD7bO5ygbHrxJUvNRwJM5sXRK1Y/jrohDqr0pcKGFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}