SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d33ad59dec454d12cbdc29f2f542915339393899253edc7e1134259585e554' 
  AND token = 'lpYO1IZHD4yoJgLHT9MwuxNvv4YpyozmjwsuotjS2YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}