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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2686168e5697162d980ab86532fc77c36f7e251eb37068164d2d0b63ed5338a4' 
  AND token = 'yOw8Exk/Q5d7/JiOSgvEO36Qpe4y2dpRktq7H1SjqVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}