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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6422e0ae8c058fa61eee1c43cc8df0dc4bac0465c524266c4afcf3231cf40b11' 
  AND token = 'r25rTsOC/aYYDXaALlKaj2795SbAhIkAI3wxWDt6diQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}